{"id":18638,"date":"2020-01-30T14:35:20","date_gmt":"2020-01-30T13:35:20","guid":{"rendered":"https:\/\/devhml.givememore.net\/recherche-et-formation\/les-domaines-de-la-recherche\/"},"modified":"2022-03-28T16:58:58","modified_gmt":"2022-03-28T14:58:58","slug":"les-domaines-de-la-recherche","status":"publish","type":"page","link":"https:\/\/devhml.givememore.net\/recherche-et-innovation\/les-domaines-de-la-recherche\/","title":{"rendered":"Les domaines de la recherche"},"content":{"rendered":"\n
\"\"<\/figure><\/div>\n\n\n\n

<\/p>\n\n\n\n

La recherche du progr\u00e8s au service des malades est inscrite dans l\u2019origine m\u00eame de l\u2019H\u00f4pital Marie-Lannelongue. Recherche acad\u00e9mique et activit\u00e9 m\u00e9dico-chirurgicale de pointe vont ici de pair et construisent un mod\u00e8le d\u2019innovation original, particuli\u00e8rement efficace.<\/strong><\/p>\n\n\n\n

Acteur atypique au sein du monde de la recherche, Marie Lannelongue a d\u00e8s sa cr\u00e9ation affirm\u00e9 sa double vocation : soigner et d\u00e9couvrir. Son histoire est jalonn\u00e9e de grandes premi\u00e8res : transplantation c\u0153ur-poumons, correction de la transposition des gros vaisseaux, chirurgie de la trach\u00e9e\u2026 Aujourd\u2019hui, l\u2019\u00e9tablissement d\u00e9veloppe, autour des th\u00e9matiques qui ont fait sa r\u00e9putation, des approches compl\u00e9mentaires. Sa force : savoir associer recherche fondamentale, innovation chirurgicale, recherche clinique et m\u00e9decine translationnelle en mettant au centre de ses travaux les probl\u00e9matiques cliniques rencontr\u00e9es par les m\u00e9decins et chirurgiens chez les malades qu\u2019ils suivent et op\u00e8rent.<\/p>\n\n\n\n

Trois unit\u00e9s de recherches<\/h2>\n\n\n\n

Ainsi, Marie Lannelongue abrite depuis 2010 l\u2019unit\u00e9 mixte Inserm\/universit\u00e9 Paris-Sud U999, \u00ab Hypertension art\u00e9rielle pulmonaire : physiopathologie et innovation th\u00e9rapeutique \u00bb. Leader sur ces sujets, cette unit\u00e9 d\u00e9veloppe, sous la direction du Pr Marc Humbert, des projets de recherche fondamentale et de recherche clinique autour de l\u2019hypertension art\u00e9rielle pulmonaire.<\/p>\n\n\n\n

Au sein de Marie Lannelongue, un laboratoire de recherche chirurgicale fait vivre la tradition d\u2019innovation de l\u2019\u00e9tablissement en d\u00e9veloppant de nouvelles techniques chirurgicales de transplantation pulmonaire et cardio-pulmonaire. Dirig\u00e9e par le Pr \u00c9lie Fadel, l\u2019\u00e9quipe du laboratoire met au point et teste des techniques chirurgicales, de nouveaux traitements et dispositifs m\u00e9dicaux, pour am\u00e9liorer toujours davantage le service apport\u00e9 aux malades. L\u2019\u00e9quipe est \u00e9galement engag\u00e9e dans un programme de th\u00e9rapie g\u00e9nique avec une \u00e9quipe de l\u2019Inserm, U986, dirig\u00e9e par les Prs Bougn\u00e8res et Fradin. Enfin, l\u2019unit\u00e9 de recherche clinique, dirig\u00e9e par le Pr Olaf Mercier, est pleinement int\u00e9gr\u00e9e \u00e0 la direction de la recherche et de l\u2019innovation de l\u2019\u00e9tablissement.<\/p>\n\n\n\n

Cette int\u00e9gration permet de mettre en place rapidement et efficacement les \u00e9tudes cliniques n\u00e9cessaires pour qu\u2019une innovation m\u00e9dicale ou chirurgicale puisse \u00eatre approuv\u00e9e par les autorit\u00e9s de sant\u00e9 et d\u00e9ploy\u00e9e au b\u00e9n\u00e9fice des malades.
Les recherches men\u00e9es au sein de cette unit\u00e9 font, chaque ann\u00e9e, l\u2019objet de dizaines de publications scientifiques internationales et de communications dans des congr\u00e8s en France et \u00e0 l\u2019\u00e9tranger. Dans le domaine de la chirurgie cardiaque et thoracique, Marie Lannelongue est ainsi l\u2019un des rares \u00e9tablissements fran\u00e7ais \u00e0 pr\u00e9senter r\u00e9guli\u00e8rement, depuis sa cr\u00e9ation, des communications dans les plus grands congr\u00e8s internationaux.<\/p>\n\n\n\n

Des donn\u00e9es utiles \u00e0 tous<\/h2>\n\n\n\n

Marie Lannelongue dispose d\u2019un service d\u2019anatomopathologie, dirig\u00e9 par le Dr Vincent Thomas de Montpr\u00e9ville, dont l\u2019activit\u00e9 est en forte \u00e9volution, \u00e0 l\u2019image de celle des diff\u00e9rents p\u00f4les de l\u2019\u00e9tablissement. Le service dispose d\u2019une importante tumoroth\u00e8que, Centre de Ressource Biologique, riche de plus de 13 500 \u00e9chantillons, qui est int\u00e9gr\u00e9e dans le r\u00e9seau des banques de tissus. Reconnue comme centre formateur, elle accueille des internes en formation. Le service d\u2019anatomopathologie est activement impliqu\u00e9 dans la recherche sur les maladies vasculaires pulmonaires men\u00e9e au sein de l\u2019unit\u00e9 Inserm 999 et du laboratoire de recherche chirurgicale de Marie Lannelongue.
Il a \u00e9galement nou\u00e9 des collaborations internationales avec des \u00e9tablissements d\u2019enseignement et de recherche en Grande-Bretagne, aux Pays-Bas et en Allemagne.<\/p>\n\n\n\n

Demain, innover autrement<\/h2>\n\n\n\n

Les \u00e9quipes de Marie Lannelongue anticipent \u00e9galement les grandes \u00e9volutions scientifiques et techniques de demain. Elles ont toujours travaill\u00e9 en \u00e9troite collaboration avec les ing\u00e9nieurs et les industriels et continuent de le faire pour d\u00e9velopper des dispositifs m\u00e9dicaux innovants qui feront l\u2019objet de brevets. Le projet Bio-Art Lung 2020, men\u00e9 en partenariat avec plusieurs groupes industriels dont Airbus Industrie et retenu parmi les projets de recherche hospitalo-universitaire en sant\u00e9 (RHU) dans le cadre du programme d\u2019investissements d\u2019avenir du Gouvernement, en est un exemple, ainsi que Kardiozis, une holding incubatrice cr\u00e9\u00e9e en 2011 et qui travaille, \u00e0 partir d\u2019un brevet d\u00e9pos\u00e9 par Marie Lannelongue, sur une proth\u00e8se endovasculaire innovante destin\u00e9e au traitement des an\u00e9vrismes aortiques, dans le but d\u2019am\u00e9liorer la qualit\u00e9 de vie et la survie des patients implant\u00e9s \u00e0 long terme.
Autre piste d\u2019avenir : la simulation et la chirurgie guid\u00e9e par l\u2019image.
La formation des jeunes chirurgiens \u00e9volue et le temps pass\u00e9 au lit du malade diminue. Le recours \u00e0 des simulateurs, \u00e0 la fois pour l\u2019apprentissage et la transmission des gestes chirurgicaux et pour la diffusion de techniques innovantes, est appel\u00e9 \u00e0 se d\u00e9velopper fortement.<\/p>\n","protected":false},"excerpt":{"rendered":"

La recherche du progr\u00e8s au service des malades est inscrite dans l\u2019origine m\u00eame de l\u2019H\u00f4pital Marie-Lannelongue. Recherche acad\u00e9mique et activit\u00e9 m\u00e9dico-chirurgicale de pointe vont ici de pair et construisent un mod\u00e8le d\u2019innovation original, particuli\u00e8rement efficace. Acteur atypique au sein du monde de la recherche, Marie Lannelongue a d\u00e8s sa cr\u00e9ation affirm\u00e9 sa double vocation : 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