{"id":18838,"date":"2020-02-05T09:13:30","date_gmt":"2020-02-05T08:13:30","guid":{"rendered":"https:\/\/devhml.givememore.net\/specialites\/greffes\/cardiaque\/"},"modified":"2022-02-10T15:17:08","modified_gmt":"2022-02-10T14:17:08","slug":"cardiaque","status":"publish","type":"service","link":"https:\/\/devhml.givememore.net\/specialites\/greffes\/cardiaque\/","title":{"rendered":"Transplantation cardiaque"},"content":{"rendered":"\n

Depuis janvier 1988, plus de 350 patients ont b\u00e9n\u00e9fici\u00e9 d\u2019une transplantation cardiaque \u00e0 l\u2019H\u00f4pital Marie-Lannelongue, dont 60 enfants et 37 adultes ayant une cardiopathie cong\u00e9nitale.<\/strong><\/p>\n\n\n\n

La premi\u00e8re transplantation cardiaque chez le nouveau-n\u00e9 en France, a \u00e9t\u00e9 r\u00e9alis\u00e9e \u00e0 l’H\u00f4pital Marie-Lannelongue en 1988 chez un enfant de 6 jours.<\/strong><\/p>\n\n\n\n

L’H\u00f4pital Marie-Lannelongue est une \u00ab structure \u00e0 \u00e9chelle humaine \u00bb ce qui permet un suivi personnalis\u00e9 de l\u2019enfance \u00e0 l\u2019\u00e2ge adulte des patients transplant\u00e9s cardiaques.<\/p>\n\n\n\n

L’H\u00f4pital Marie-Lannelongue est le seul centre de transplantation cardiaque en Ile-de-France \u00e0 avoir une activit\u00e9 de greffe cardiaque mixte adulte et enfants, et le seul avec Necker-Enfants Malades \u00e0 r\u00e9aliser des transplantations cardiaques p\u00e9diatriques, au sein du centre de r\u00e9f\u00e9rence fran\u00e7ais des cardiopathies cong\u00e9nitales complexes M3C.<\/p>\n\n\n\n

Ceci s\u2019int\u00e8gre dans la sp\u00e9cificit\u00e9 de l’H\u00f4pital Maire-Lannelongue concernant la prise en charge des patients cong\u00e9nitaux adultes, la transplantation dans cette population posant des probl\u00e8mes particuliers (complexit\u00e9 de l\u2019anatomie cardiaque, nombreuses chirurgies pr\u00e9alables, difficult\u00e9s immunologiques).<\/p>\n\n\n\n

Des techniques d\u2019assistance circulatoire temporaire<\/a><\/span> sont parfois mises en place en attente de greffe.<\/p>\n\n\n\n

L’H\u00f4pital Marie-Lannelongue est pionnier en mati\u00e8re de surveillance des transplant\u00e9s cardiaques : le d\u00e9pistage des rejets aigus se fait uniquement sur l\u2019\u00e9chocardiographie-doppler, et non par les biopsies endomyocardiques.<\/p>\n\n\n\n

De m\u00eame, le rejet chronique est d\u00e9pist\u00e9 par l\u2019angioscanner coronaire, et non par la coronarographie, dans le but d\u2019\u00e9viter au maximum les proc\u00e9dures invasives chez ces patients. L\u2019observance th\u00e9rapeutique, cl\u00e9 de la long\u00e9vit\u00e9 du greffon, est ainsi facilit\u00e9e.<\/p>\n\n\n\n

L\u2019organisation des bilans pr\u00e9-transplantations, la prise en charge des transplant\u00e9s cardiaques, les consultations sp\u00e9cialis\u00e9es pr\u00e9-et post-greffe sont assur\u00e9es par le Dr Nidal BEN MOUSSA (transplantation cardiaque p\u00e9diatrique et cong\u00e9nitale) et le Dr Ngoc-Tram TO (transplantation cardiaque adulte).<\/p>\n\n\n\n

Un programme de pr\u00e9servation du greffon cardiaque sur machine transportable de perfusion ex vivo a \u00e9t\u00e9 initi\u00e9 \u00e0 l\u2019H\u00f4pital Marie Lannelongue en 2019 sous la direction de l\u2019\u00e9quipe de chirurgie cardiaque adulte. Cette technologie innovante a pour objectif d\u2019augmenter les chances de transplantation en permettant une pr\u00e9servation prolong\u00e9e avec une \u00e9valuation continue de la viabilit\u00e9 de l\u2019organe jusqu\u2019\u00e0 sa transplantation. Ce programme s\u2019accompagne d\u2019un protocole de recherche translationnel conduit au sein du laboratoire de recherche avec l\u2019objectif de permettre l\u2019ouverture de la transplantation cardiaque en France \u00e0 partir de donneurs d\u00e9c\u00e9d\u00e9s d\u2019arr\u00eat cardiaque contr\u00f4l\u00e9 (Maastricht 3).<\/p>\n\n\n\n

\"\"<\/figure>\n","protected":false},"excerpt":{"rendered":"

Depuis janvier 1988, plus de 350 patients ont b\u00e9n\u00e9fici\u00e9 d\u2019une transplantation cardiaque \u00e0 l\u2019H\u00f4pital Marie-Lannelongue, dont 60 enfants et 37 adultes ayant une cardiopathie cong\u00e9nitale. La premi\u00e8re transplantation cardiaque chez le nouveau-n\u00e9 en France, a \u00e9t\u00e9 r\u00e9alis\u00e9e \u00e0 l’H\u00f4pital Marie-Lannelongue en 1988 chez un enfant de 6 jours. L’H\u00f4pital Marie-Lannelongue est une \u00ab structure \u00e0 […]<\/p>\n","protected":false},"author":22,"featured_media":0,"parent":18525,"menu_order":2,"template":"","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"etablissements":[],"services":[],"class_list":["post-18838","service","type-service","status-publish","hentry"],"acf":[],"featured_img":false,"coauthors":[],"author_meta":{"author_link":"https:\/\/devhml.givememore.net\/author\/charlotte-gmm\/","display_name":"Charlotte"},"relative_dates":{"created":"Publi\u00e9 6 ans il y a","modified":"Mis \u00e0 jour 4 ans il y a"},"absolute_dates":{"created":"Publi\u00e9 le 5 f\u00e9vrier 2020","modified":"Mise \u00e0 jour le 10 f\u00e9vrier 2022"},"absolute_dates_time":{"created":"Publi\u00e9 le 5 f\u00e9vrier 2020 9 h 13 min","modified":"Mise \u00e0 jour le 10 f\u00e9vrier 2022 15 h 17 min"},"featured_img_caption":"","tax_additional":{"etablissements":{"linked":[],"unlinked":[],"slug":"etablissements","name":"\u00c9tablissements"},"services":{"linked":[],"unlinked":[],"slug":"services","name":"Services"}},"series_order":"","_links":{"self":[{"href":"https:\/\/devhml.givememore.net\/api\/wp\/v2\/service\/18838","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/devhml.givememore.net\/api\/wp\/v2\/service"}],"about":[{"href":"https:\/\/devhml.givememore.net\/api\/wp\/v2\/types\/service"}],"version-history":[{"count":0,"href":"https:\/\/devhml.givememore.net\/api\/wp\/v2\/service\/18838\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/devhml.givememore.net\/api\/wp\/v2\/service\/18525"}],"wp:attachment":[{"href":"https:\/\/devhml.givememore.net\/api\/wp\/v2\/media?parent=18838"}],"wp:term":[{"taxonomy":"etablissements","embeddable":true,"href":"https:\/\/devhml.givememore.net\/api\/wp\/v2\/etablissements?post=18838"},{"taxonomy":"services","embeddable":true,"href":"https:\/\/devhml.givememore.net\/api\/wp\/v2\/services?post=18838"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}